Primitive myxoid mesenchymal tumor of infancy. Review of literature

Primitive myxoid mesenchymal tumor of infancy (PMMTI) is an aggressive with a high rate local recurrence, rare metastasis and poor response to chemotherapy.PMMTI soft-tissue sarcoma that preferentially affects infants. It isolated from the group infantile fibrosarcomas or myofibroblastic tumors. PMMTI differs other tumors in clinical course, morphological features primarily molecular genetic changes. ETV6-NTRK3 gene fusion characteristic fibrosarcomas. However, it not detected patients PMMTI. BCOR ITD had been described allowed define this fibrosarcomas.Unified treatment approaches have identified for yet. Radical surgical removal preferred treatment. target. Nowadays search targeted drugs ongoing could help solve problem